prime-editing

Prime editing guide RNA prediction

A declarative DSL and compiler for reproducible gene-editing design — with LLM agents and an MCP server so any AI agent can drive it safely.

A variant-first, multi-modality CRISPR design framework that unifies SpCas9 nuclease, base-editor, and prime-editor chemistries under a single typed interface to deliver ranked candidate edits complete with calibrated uncertainty intervals, predicted outcome distributions, and ancestry-stratified, population-aware off-target safety reporting.

Materials for the Harvard 2026 genetics bootcamp for CRISPR screening presented by Rich Sherwood's lab.

Python code used to scan genomic sequences and calculate Hamming distance to identify near-matching DNA regions.

Repository for the code used to generate figures for Zhou et al. and running the BEAN-FUSE pipeline.

Computational pipeline for designing celiac-safe wheat by editing gluten genes to remove TG2 deamidation sites

PROpeg — precision-optimized pegRNA design and structure visualization tool for plant prime editing (ICAR-CRRI & ICAR-IASRI)

AI-assisted platform for designing CRISPR experiments — from target selection to bench-ready protocols

Cross-method single-base m⁶A curation and computational prime-editing pegRNA candidates; code and QC only, row-level data pending.

In-silico CRISPR target-selection research for color blindness — disease-class dossiers, ranked edit targets (C203R base editing, hybrid exon-5 prime editing), and an evidence-cited review paper.

Division-coupled DNA recorders carry a built-in early bias in human cortical organoids: simulator, analysis, figures and released results

Prime Medicine — independent third-party profile of a public API surface, by API Evangelist. Prime Medicine is a clinical-stage biotechnology company developing a new class of differentiated one-time curative genetic therapies built on Prime Editing, a versatile, precise, and efficient gene editing technology that can search and replace disease-cau