Bioinformatics and scientific computing professional working across biological data, reproducible workflows, scientific software, and research instrumentation.
I turn complex research questions and experimental data into clear analyses, reusable workflows, and practical tools. My experience spans genomics and transcriptomics, quantitative data analysis, HPC, scientific applications, spectroscopy, and laboratory-facing software.
Currently a Researcher I at the University of Tennessee Health Science Center. M.S. Bioinformatics, Brandeis University (2024); B.S. Biology, University of Memphis (2021).
- Biological data and computation — RNA-seq, single-cell analysis, viral genomics, and variant analysis.
- Reproducible workflows — R, Python, Nextflow/nf-core, SLURM/HPC, containers, testing, and validation.
- Scientific software — data-processing tools, interactive analysis, and scientific visualization.
- Instrumentation and applied analysis — spectroscopy, signal processing, simulated acquisition, and hardware/software integration.
Viral intra-host variant workflow — Containerized Nextflow DSL2 pipeline for viral intra-host variant calling, quasispecies haplotype reconstruction, and evolutionary selection analysis. Tested on synthetic fixtures with an end-to-end Nextflow test suite.
LIBS spectroscopy workbench — Python workbench for spectral processing, baseline correction, elemental line identification, and simulated acquisition.
Tiling amplicon primer design — Python package for designing tiled amplicon primer schemes for NGS of small viral genomes, including primer QC and pooling assignment.
Preclinical study analysis — Modular R/Shiny application for longitudinal animal-study data, survival analysis, and report export.
- Lab bioinformatics templates — Reusable R, Python, and Quarto templates using synthetic example data. Rendered gallery
- Akodon genome assembly workflow — SLURM pipeline for genome assembly and gene prediction on HPC.
- Alphavirus RNA-seq wrapper — SLURM execution wrapper and preflight validation layer for nf-core/rnaseq.
- Email: aleponce92@gmail.com
Open to roles in bioinformatics, scientific computing, research software, scientific data analysis, and applied R&D.
Public repositories here are released under MIT, except libs-spectroscopy-workbench, which is GPLv3. Commercial instrument software, trained model weights, vendor hardware SDKs, and client datasets are maintained privately and are not part of this profile.